Tandem mass spectrometry in physiology.
نویسندگان
چکیده
Tandem mass spectrometry coupled to liquid chromatography (LC-MS/MS) allows identification of proteins in a complex mixture without need for protein purification ("shotgun" proteomics). Recent progress in LC-MS/MS-based quantification, phosphoproteomic analysis, and targeted LC-MS/MS using multiple reaction monitoring (MRM) has made LC-MS/MS a powerful tool for the study of cell physiology.
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ورودعنوان ژورنال:
- Physiology
دوره 22 شماره
صفحات -
تاریخ انتشار 2007